PAMAM Dendrimer G0.0 amine - CAS 155773-72-1

PAMAM Dendrimer G0.0 amine functions as a pore-forming channel antagonist, affecting anthrax toxin protective antigen 63 (PA63, IC50 of 231 nM) and Clostridium botulinum C2 toxin subunit (C2IIa, IC50 of 940 nM) . At 10 and 20 μM concentrations, it reduces HeLa cell death induced by C2 toxin. Additionally, PAMAM Dendrimer G0.0 amine acts as a nickel chelator. When combined with a chitosan complex on polysulfone membranes, it selectively captures and stores carbon dioxide (CO2) in gas feed systems. It is utilized in synthesizing PAMAM Dendrimer G0.5 Carboxylate (CAS 339334-01-9) and PAMAM Dendrimer G1.0 Amine (CAS 142986-44-5) . This compound is applicable in research related to infection, cancer, and drug delivery systems.

Antibacterial, Antibiotic

Microbiology/Virology

155700

C22H48N10O4

516.68

O=C(NCCN)CCN(CCC(=O)NCCN)CCN(CCC(=O)NCCN)CCC(=O)NCCN

-20°C

Ice Packs

Small Compound