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Pamapimod - CAS 449811-01-2

Pamapimod - CAS 449811-01-2

SKU:MF-0094961-01

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  • Bioactivity

    Pamapimod (R1503) (R-1503, Ro4402257) is a novel, selective inhibitor of p38 mitogen-activated protein kinase. It inhibits p38α and p38β enzymatic activity with IC50 values of 0.014±0.002 and 0.48± 0.04 microM, respectively with no activity against p38delta or p38 gamma isoforms.

  • Target

    Autophagy, p38 MAPK

  • Related Pathways

    MAPK, Autophagy

  • CAS Number

    449811-01-2

  • Purity

    0.9999

  • Molecular Formula

    C19H20F2N4O4

  • Molecular Weight

    406.38

  • SMILES

    Cn1c2nc(NC(CCO)CCO)ncc2cc(Oc2ccc(F)cc2F)c1=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound