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Pamiparib - CAS 1446261-44-4

Pamiparib - CAS 1446261-44-4

SKU:MF-0019435-01

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  • Bioactivity

    Pamiparib (BGB-290) is an orally active, potent, highly selective PARP inhibitor with IC50 values of 0.9 nM for PARP1 and 0.5 nM for PARP2. It exhibits strong PARP trapping, has the capability to penetrate the brain, and is used for researching various cancers, including solid tumors.

  • Target

    PARP

  • Related Pathways

    DNA Damage/DNA Repair, Chromatin/Epigenetic

  • CAS Number

    1446213

  • Purity

    0.9969

  • Molecular Formula

    C16H15FN4O

  • Molecular Weight

    298.31

  • SMILES

    C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound