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Molfinity

Pamiparib maleate - CAS 2086689-94-1

Pamiparib maleate - CAS 2086689-94-1

SKU:MF-0000090-01

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  • Bioactivity

    Pamiparib is a highly potent and selective PARP inhibitor. BGB-290 selectively binds to PARP and prevents PARP-mediated repair of single-strand DNA breaks via the base-excision repair (BER) pathway. This enhances the accumulation of DNA strand breaks, promotes genomic instability, and eventually leads to apoptosis.

  • Target

    Others, Apoptosis

  • Related Pathways

    Apoptosis, Others

  • CAS Number

    2086689-94-1

  • Molecular Formula

    C44H42F2N8O14

  • Molecular Weight

    944.859

  • SMILES

    OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34.C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound