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Pamiparib maleate - CAS 2086689-94-1
Pamiparib maleate - CAS 2086689-94-1
SKU:MF-0000090-01
Regular price
$2,041.92 USD
Regular price
$1,475.50 USD
Sale price
$2,041.92 USD
Taxes included.
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Product Details
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Bioactivity
Pamiparib is a highly potent and selective PARP inhibitor. BGB-290 selectively binds to PARP and prevents PARP-mediated repair of single-strand DNA breaks via the base-excision repair (BER) pathway. This enhances the accumulation of DNA strand breaks, promotes genomic instability, and eventually leads to apoptosis.
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Target
Others, Apoptosis
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Related Pathways
Apoptosis, Others
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CAS Number
2086689-94-1
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Molecular Formula
C44H42F2N8O14
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Molecular Weight
944.859
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SMILES
OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34.C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound