PAMP-12 (unmodified) - CAS 929905-12-4

PAMP-12 (unmodified), an endogenous peptide and potent MRGPRX2 (MrgX2) agonist (EC50=20-50 nM), induces hypotension by inhibiting catecholamine release from sympathetic nerve endings and adrenal chromaffin cells [1].

MRGPR

GPCR/G Protein

929889

C77H118N24O15

1619.91

C([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CC1=CC=CC=C1)N)=O)CCCNC(=N)N)=O)CCCCN)=O)CCCCN)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CC=2C=3C(NC2)=CC=CC3)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CO)=O)CC(C)C)=O)C)=O)=O)CCCCN)=O)CC(N)=O)=O)C=4C=5C(NC4)=CC=CC5

-20°C

Ice Packs

Peptide