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Pamufetinib - CAS 1190836-34-0

Pamufetinib - CAS 1190836-34-0

SKU:MF-0017713-01

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  • Bioactivity

    Pamufetinib (TAS-115) is a potent kinase inhibitor targeting VEGFR and the hepatocyte growth factor receptor (c-Met/HGFR), with IC50s of 30 nM for rVEGFR2 and 32 nM for rMET, respectively.

  • Target

    VEGFR, c-Met/HGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    1190802

  • Purity

    0.9939

  • Molecular Formula

    C27H23FN4O4S

  • Molecular Weight

    518.56

  • SMILES

    O(C=1C2=C(C=C(OC)C(C(NC)=O)=C2)N=CC1)C3=C(F)C=C(NC(NC(CC4=CC=CC=C4)=O)=S)C=C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound