PAN endonuclease-IN-1 - CAS 2378640-67-4

Compound 23, also known as PAN endonuclease-IN-1, demonstrates potent inhibitory activity against PAN endonuclease, a vital element of the influenza virus replication machinery and a significant antiviral target [1]. It exhibits dissociation constants (Kd) of 277 μM, 384 μM, and 328 μM for the wild type (WT), I38T, and E23K variants of PAN endonuclease respectively.

Influenza Virus

Microbiology/Virology

2378640-67-4

C14H8F3N5O4

367.24

C(F)(F)(F)C1=C(C=CC(=C1)C=2NN=NN2)C=3NC(C(O)=O)=C(O)C(=O)C3

-20°C

Ice Packs

Small Compound