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Pan-HCN-IN-1 - CAS 1334308-63-2

Pan-HCN-IN-1 - CAS 1334308-63-2

MF-0121111-01

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Product Details

  • Bioactivity

    Pan-HCN-IN-1 (Compound J&J12e) is an inhibitor of the hyperpolarization-activated and cyclic-nucleotide-gated 1 (HCN1) ion channel, with an IC50 of 58 nM. Pan-HCN-IN-1 reduces the voltage sag response and enhances EPSP summation in ex vivo rat brain slices [1].

  • Target

    HCN Channel

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    1334308-63-2

  • Molecular Formula

    C23H37N3O2

  • Molecular Weight

    387.56

  • SMILES

    C(NC(=O)C1=C(OCC)C=CC=C1)C2(CCCCC2)N3CCN(C(C)C)CC3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound