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Molfinity

Pan-KRAS degrader 1 - CAS 2937327-83-6

Pan-KRAS degrader 1 - CAS 2937327-83-6

SKU:MF-0142581-01

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  • Bioactivity

    Pan-KRAS degrader 1 (Compound 1) is a broad-spectrum KRAS degrader, exhibiting an inhibitory constant Ki value of 25 nM against KRASG12V as determined by surface plasmon resonance (SPR) . Additionally, this compound demonstrates antitumor activity.

  • Target

    Ras

  • Related Pathways

    GPCR/G Protein, MAPK

  • CAS Number

    2937238

  • Molecular Formula

    C22H26N8OS

  • Molecular Weight

    450.56

  • SMILES

    C[C@]1(C2=C(SC(N)=C2C#N)CCC1)C3=NC(=NO3)C4=NC(=NC=C4)N5[C@@H](C)CNCCC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound