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Pan-KRAS degrader 1 - CAS 2937327-83-6
Pan-KRAS degrader 1 - CAS 2937327-83-6
SKU:MF-0142581-01
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$2,787.80 USD
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$2,787.80 USD
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Product Details
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Bioactivity
Pan-KRAS degrader 1 (Compound 1) is a broad-spectrum KRAS degrader, exhibiting an inhibitory constant Ki value of 25 nM against KRASG12V as determined by surface plasmon resonance (SPR) . Additionally, this compound demonstrates antitumor activity.
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Target
Ras
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Related Pathways
GPCR/G Protein, MAPK
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CAS Number
2937238
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Molecular Formula
C22H26N8OS
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Molecular Weight
450.56
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SMILES
C[C@]1(C2=C(SC(N)=C2C#N)CCC1)C3=NC(=NO3)C4=NC(=NC=C4)N5[C@@H](C)CNCCC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound