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Molfinity
Pan-KRAS-IN-13 - CAS 3033637-76-9
Pan-KRAS-IN-13 - CAS 3033637-76-9
SKU:MF-0117218-01
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Product Details
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Bioactivity
Pan-KRAS-IN-13 (compound 2) is a potent inhibitor of KRAS, exhibiting IC50 values of 2.75 nM and 2.89 nM for its G12D and G12V mutations, respectively.
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Target
Ras
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Related Pathways
MAPK
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CAS Number
3033552
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Molecular Formula
C33H31F3N6O3
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Molecular Weight
616.63
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SMILES
FC1=C2C=3C(N4[C@@](CCOC3N=C1C=5C6=C(C=C(O)C5)C=CC(F)=C6C#C)(CNCC4)[H])=NC(OC[C@@]78N(C[C@H](F)C7)CCC8)=N2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound