Molfinity

Pan-KRAS-IN-4 - CAS 2885961-55-5

SKU:MF-0157468-01

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Size 5 mg 50 mg

Product Details

Bioactivity
Pan-KRAS-IN-4 (compound 5) is a potent KRAS inhibitor, demonstrating IC50 values of 0.37 nM for Kras G12C and 0.19 nM for Kras G12V [1].
Target
Ras
Related Pathways
GPCR/G Protein, MAPK
CAS Number
2885901
Molecular Formula
C36H34F2N6O3
Molecular Weight
636.69
SMILES
C(#C)C=1C=2C(=CC(O)=CC2C=CC1F)C3=C(F)C4=C(C=N3)C(=NC(OCC56N(CCC5)CCC6)=N4)N7CC8N(C(C=C)=O)C(C7)CC8
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound