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PAR4 antagonist 3 - CAS 3057206-40-0

PAR4 antagonist 3 - CAS 3057206-40-0

MF-0117131-01

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Product Details

  • Bioactivity

    PAR4 antagonist3 (Compound 36) is a selective antagonist of protease-activated receptor 4 (PAR4) . It exhibits antiplatelet activity with an IC50 of 26.1 nM and enhances metabolic stability in human liver microsomes, with a half-life (T1/2) of 97.6 minutes.

  • Target

    Protease-activated Receptor

  • Related Pathways

    GPCR/G Protein

  • CAS Number

    3057166

  • Molecular Formula

    C22H16FN3O5S

  • Molecular Weight

    453.44

  • SMILES

    FC1=CC=C(OCC2OC3=C(OC2)C=CC=4C=C(OC34)C=5N=C6SC(=NN6C5)OC)C=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound