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PAR4 antagonist 4 - CAS 3057206-41-1

PAR4 antagonist 4 - CAS 3057206-41-1

MF-0117138-01

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Product Details

  • Bioactivity

    PAR4 antagonist4 (Compound 37) is a selective antagonist of protease-activated receptor 4 (PAR4) . It exhibits antiplatelet activity with an IC50 of 14.2 nM. Moreover, PAR4 antagonist3 enhances metabolic stability in human liver microsomes, showing a half-life (T1/2) of 42.5 minutes.

  • Target

    Protease-activated Receptor

  • Related Pathways

    GPCR/G Protein

  • CAS Number

    3057164

  • Molecular Formula

    C22H16FN3O5S

  • Molecular Weight

    453.44

  • SMILES

    FC1=CC=C(OCC2OC=3C=CC=4C=C(OC4C3OC2)C=5N=C6SC(=NN6C5)OC)C=C1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound