Paraxanthine - CAS 611-59-6

Paraxanthine (1,7-dimethylxanthine) is a metabolite of caffeine (sc-202514) which functions as an adenosine receptor ligand and a PARP-1 inhibitor in pulmonary epithelial cells. Studies suggest that Paraxanthine is structurally similar to caffeine and possibly mediates the physiological effects of caffeine. Also Paraxanthine acts as a competitive phosphodiesterase inhibitor, which increases intracellular cAMP, activates PKA, inhibits TNF-α and leukotriene synthesis. In addition, Paraxanthine acts as a Na+/K+ ATPase enzymatic effector.

Endogenous Metabolite, Drug Metabolite

Metabolism

546

0.9999

C7H8N4O2

180.16

Cn1cnc2[nH]c(=O)n(C)c(=O)c12

-20°C

Ice Packs

Natural Product