PARG-IN-6 - CAS 3083070-66-7

PARG-IN-6 (Compound 2) is an orally bioavailable PARG inhibitor with an IC50 of 0.3 nM. It exhibits significant anticancer activity against cancer cells, with an IC50 of 0.0368 μM for HCC1395 cells. PARG-IN-6 shows potential for research in colon cancer, appendiceal cancer, and pancreatic cancer.

Poly (ADP-ribose) Glycohydrolase (PARG)

Cell Cycle/Checkpoint

3082997

C24H25F4N7O4S3

647.69

N#CC1(NS(=O)(=O)C2=CC=3C(=NN(C3C(=C2F)C4=C(C)CN(CC4)S(=O)(=O)C(C)C)C)C5=NN=C(S5)C(F)(F)F)CC1

-20°C

Ice Packs

Small Compound