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PARP-1-IN-2 - CAS 684234-55-7

PARP-1-IN-2 - CAS 684234-55-7

MF-0093315-01

$40.65 USD
$40.65 USD
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Product Details

  • Bioactivity

    PARP-1-IN-2 is a potent PARP1 inhibitor that crosses the blood-brain barrier (IC50: 149 nM) .PARP-1-IN-2 showed significant antiproliferative activity against the human lung adenocarcinoma epithelial cell line A549 in cellular assays.PARP-1-IN-2 induced apoptosis in A549 cells.

  • Target

    Apoptosis, Caspase, PARP

  • Related Pathways

    Proteases/Proteasome, Chromatin/Epigenetic, Apoptosis, DNA Damage/DNA Repair

  • CAS Number

    684172

  • Purity

    0.9932

  • Molecular Formula

    C22H15Cl2N3O2

  • Molecular Weight

    424.28

  • SMILES

    Clc1ccc(cc1)-c1nn(CC(=O)Nc2cccc(Cl)c2)c(=O)c2ccccc12

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound