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PARP-1-IN-23 - CAS 2976497-48-8

PARP-1-IN-23 - CAS 2976497-48-8

SKU:MF-0148302-01

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  • Bioactivity

    PARP-1-IN-23 (Compound I16) is an orally bioavailable, selective inhibitor of PARP-1, exhibiting an IC50 of 12.38 nM. This compound demonstrates efficacy in inhibiting tumor growth in vivo.

  • Target

    PARP

  • Related Pathways

    Chromatin/Epigenetic, DNA Damage/DNA Repair

  • CAS Number

    2976497-48-8

  • Molecular Formula

    C22H18BrN3O5S

  • Molecular Weight

    516.36

  • SMILES

    O=C(N)C=1C=CC=C2N=C(NC21)C=3C=C(Br)C(OS(=O)(=O)C=4C=CC=CC4C)=C(OC)C3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound