PARP-1-IN-3 - CAS 2976342-33-1

PARP-1-IN-3 is a potent PARP-1 inhibitor that inhibits PARP-1 and PARP-2 with IC50 values of 0.25 nM and 2.34 nM, respectively.PARP-1-IN-3 has potential anti-inflammatory activity, induces apoptosis, and arrests the cell cycle in the G2/M phase.PARP-1-IN-3 may be useful for the study of cancer-related diseases. cancer-related diseases.

PARP, Caspase, Apoptosis

Chromatin/Epigenetic, Proteases/Proteasome, DNA Damage/DNA Repair, Apoptosis

2976308

0.9986

C21H17BrN2O3

425.28

O=C(N)C=1C=CC=CC1OCC=2C=CC=C(C2)NC(=O)C3=CC=C(Br)C=C3

-20°C

Ice Packs

Small Compound