PARP-2/1-IN-2 - CAS 912444-01-0

PARP-2/1-IN-2, an enantiomer of Veliparib, serves as a potent inhibitor of PARP, demonstrating inhibition constants (Kis) of 2 nM for PARP-2 and 5 nM for PARP-1. This compound exhibits a half-maximal effective concentration (EC50) of 3 nM in cell-based assays evaluating PARP activity [1].

Others, PARP

DNA Damage/DNA Repair, Chromatin/Epigenetic, Others

912444-01-0

C13H16N4O

244.29

C(N)(=O)C1=C2C(N=C(N2)[C@]3(C)CCCN3)=CC=C1

-20°C

Ice Packs

Small Compound