PARP/NAMPT-IN-1 - CAS 2755825-45-5

PARP/NAMPT-IN-1 (Compound 13j) is a dual-target inhibitor of PARP and NAMPT, with IC50 values of 0.8 nM for PARP1 and 18 nM for NAMPT. It suppresses breast cancer cell proliferation and migration, inducing apoptosis. PARP/NAMPT-IN-1 is applicable for research on triple-negative breast cancer.

Apoptosis

Apoptosis

2755775

C34H36FN7O3

609.693

O=C(NCCCCCCN1CCN(C(=O)C2=CC(=CC=C2F)CC3=NNC(=O)C=4C=CC=CC43)CC1)C=5C=CN6C=CN=C6C5

-20°C

Ice Packs

Small Compound