PARP1/BRD4-IN-1 - CAS 2758117-74-5

PARP1/BRD4-IN-1 is a highly selective and potent inhibitor of PARP1 (IC50: 49 nM) and BRD4 (IC50: 202 nM), which inhibits the expression and activity of PARP1 and BRD4, thereby synergistically suppressing the malignant growth of pancreatic cancer cells.

Apoptosis, PARP, Epigenetic Reader Domain, Others, DNA/RNA Synthesis

Apoptosis, Others, Chromatin/Epigenetic, Cell Cycle/Checkpoint, DNA Damage/DNA Repair

2758038

C29H26N6O3

506.56

C(N1C(C=2C(N(C)C1=O)=CC=C(C2)C=3C(C)=NOC3C)C4=CC=CC=C4)C=5NC=6C(N5)=CC=CC6C(N)=O

-20°C

Ice Packs

Small Compound