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PARP1-IN-14 - CAS 2098639-70-2

PARP1-IN-14 - CAS 2098639-70-2

MF-0147149-01

$1,383.80 USD
$1,383.80 USD
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Product Details

  • Bioactivity

    PARP1-IN-14 (compound 19k) is a potent PARP1 inhibitor with an IC50 of 0.6 ± 0.1 nM, displaying antiproliferative effects on MDA-MB-436 (BRCA1 −/−) and Capan-1 (BRCA2 −/−) cells, with IC50 values below 0.3 nM [1].

  • Target

    PARP, Apoptosis

  • Related Pathways

    Chromatin/Epigenetic, DNA Damage/DNA Repair, Apoptosis

  • CAS Number

    2098567

  • Molecular Formula

    C28H24FN7O3

  • Molecular Weight

    525.53

  • SMILES

    CC1N2C(=NN=C2CN(C(=O)C3=CC(CC=4C=5C(C(=O)NN4)=CC=CC5)=CC=C3F)C1)C=6N=C(OC)C=CC6

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound