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PARP1-IN-20 - CAS 2659357-95-4
PARP1-IN-20 - CAS 2659357-95-4
SKU:MF-0148059-01
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$1,910.30 USD
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$1,910.30 USD
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Product Details
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Bioactivity
PARP1-IN-20 (compound 19A10) serves as a highly effective inhibitor of PARP1, demonstrating an IC50 value of 4.62 nM, but exhibits a relatively minimal PARP-trapping effect when compared with Veliparib, where it shows an IC50 (MDA-MB-436) greater than 100 μM.
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Target
PARP
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Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
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CAS Number
2659357-95-4
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Molecular Formula
C23H19BrN6O3S
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Molecular Weight
539.4
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SMILES
O=C(N)C=1C=CC=C2N=C(NC21)C=3C=CC(=CC3)C(=O)N4CCN(C(=O)C=5N=C(Br)SC5)CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound