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Molfinity

PARP1-IN-20 - CAS 2659357-95-4

PARP1-IN-20 - CAS 2659357-95-4

SKU:MF-0148059-01

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  • Bioactivity

    PARP1-IN-20 (compound 19A10) serves as a highly effective inhibitor of PARP1, demonstrating an IC50 value of 4.62 nM, but exhibits a relatively minimal PARP-trapping effect when compared with Veliparib, where it shows an IC50 (MDA-MB-436) greater than 100 μM.

  • Target

    PARP

  • Related Pathways

    DNA Damage/DNA Repair, Chromatin/Epigenetic

  • CAS Number

    2659357-95-4

  • Molecular Formula

    C23H19BrN6O3S

  • Molecular Weight

    539.4

  • SMILES

    O=C(N)C=1C=CC=C2N=C(NC21)C=3C=CC(=CC3)C(=O)N4CCN(C(=O)C=5N=C(Br)SC5)CC4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound