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PARP1-IN-31 - CAS 684234-60-4
PARP1-IN-31 - CAS 684234-60-4
SKU:MF-0110246-01
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$39.90 USD
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$39.90 USD
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Product Details
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Bioactivity
PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC50 of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549), while upregulating caspase-3 and caspase-9, making it suitable for lung adenocarcinoma research.
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Target
Apoptosis, PARP, Caspase
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Related Pathways
Apoptosis, Chromatin/Epigenetic, Proteases/Proteasome, DNA Damage/DNA Repair
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CAS Number
684170
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Purity
0.9899
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Molecular Formula
C22H15ClFN3O2
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Molecular Weight
407.83
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SMILES
O=C(NC1=CC=C(F)C=C1)CN2N=C(C=3C=CC(Cl)=CC3)C=4C=CC=CC4C2=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound