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Molfinity

PARP1-IN-33 - CAS 2640677-68-3

PARP1-IN-33 - CAS 2640677-68-3

MF-0112560-01

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Product Details

  • Bioactivity

    PARP1-IN-33 (Example 6) is a PARP1 inhibitor with an IC50 of 0.41 nM. It demonstrates protective effects on retinal cells, exhibiting an EC50 of 0.02 nM in inhibiting hydrogen peroxide-induced MTS activity in human retinal pigment epithelial cells.

  • Target

    PARP

  • Related Pathways

    DNA Damage/DNA Repair, Chromatin/Epigenetic

  • CAS Number

    2640606

  • Molecular Formula

    C23H24ClFN4O

  • Molecular Weight

    426.91

  • SMILES

    Cl.N#CC1=CC=C(C=C1)N2CCN(CC2)CCCC3=CC=4C=CC=C(F)C4C(=O)N3

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound