PARP1-IN-39 - CAS 3054988-47-2

PARP1-IN-39 is an inhibitor of PARP1, with an IC50 value of 0.22 nM. In human breast cancer cells, its IC50 is 1.57 nM. PARP1-IN-39 is applicable for studying cancers associated with DNA repair deficiencies, such as breast, ovarian, pancreatic, and prostate cancers, particularly those with BRCA1/2 mutations.

PARP

DNA Damage/DNA Repair, Chromatin/Epigenetic

3054939

C24H19F3N8O2

508.46

O=C(NCC)C1=NC(F)=C(C=C1)N2N=C3C(=C2)CN(C3)CC4=CC=C5C(NC(=O)C6=C(F)C=NN56)=C4F

-20°C

Ice Packs

Small Compound