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PARP1-IN-43 - CAS 3066798-40-8
PARP1-IN-43 - CAS 3066798-40-8
SKU:MF-0119352-01
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Product Details
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Bioactivity
PARP1-IN-43 (Compound 5350) is a PARP1 inhibitor with an IC50 of 5 nM that can cross the blood-brain barrier (BBB) . It is useful for studying homologous recombination (HR) deficient cancers within the central nervous system (CNS) .
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Target
PARP
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Related Pathways
DNA Damage/DNA Repair, Chromatin/Epigenetic
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CAS Number
3066750
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Molecular Formula
C29H30N4O5
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Molecular Weight
514.57
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SMILES
O=C1NCC2=C1C=CC=C2C3=CC=CC=4C=C(OC43)C(=O)N5CCN(C(=O)C6CN(C(=O)C)CCC6)CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound