PAT1inh-A0030 - CAS 1030097-65-4

PAT1inh-A0030 is a selective inhibitor of PAT1 (SLC26A6) with an IC 50 value of 1.0 μM. It inhibits fluid absorption in the ileum of wild-type and cystic fibrosis (CF) mice (CftrdelF508/delF508) in a closed-loop model of intestinal fluid absorption and can be used in the study of intestinal diseases related to CF [1].

Chloride channel, Others

Membrane transporter/Ion channel, Others

1030097-65-4

C17H18N4O3

326.35

N(CC1=CC=CC=C1)(C)C2=C3C(=NC(C(OCC)=O)=N2)ON=C3C

-20°C

Ice Packs

Small Compound