PB1 - CAS 188714-28-5

PB1 is a highly-effective intracellular disulfide reducing agent with notable attributes such as excellent cell permeability, the capacity to generate a substantial intracellular concentration gradient, and remarkable stability. It serves as a borane-protected TCEP (tris (2-carboxyethyl) phosphine) analogue. PB1 demonstrates the potential to enhance the survival of retinal ganglion cells following axotomy in vitro at concentrations in the nanomolar and picomolar range. Consequently, PB1 has proven instrumental in the study of neuroprotective properties[1][2][3].

Others, ERK

Others, MAPK

188681

C14H22BO4P

296.11

[P](CCC(OC)=O)(CCC(OC)=O)([B+3]([H-])([H-])[H-])C1=CC=CC=C1

-20°C

Ice Packs

Small Compound