PBD dimer-2 - CAS 145325-57-1

PBD dimer-2 (compound 2c), a C8-linked pyrrolobenzodiazepine dimer, has the capability to span an extra base pair and cross-link the 5′-Pu-GA (T/A) TC-Py sequence. It serves as a potential payload for antibody–agent conjugates (ADCs) and is under research for cancer treatments [1] [2].

ADC Cytotoxin

Antibody-drug Conjugate/ADC Related

145325-57-1

C31H36N4O6

560.64

O=C1C=2C(=CC(OCCCCCOC3=C(OC)C=C4C(=C3)N=C[C@]5(N(C4=O)CCC5)[H])=C(OC)C2)N=C[C@]6(N1CCC6)[H]

-20°C

Ice Packs

Small Compound