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PBD-monoamide - CAS 2093165-00-3

PBD-monoamide - CAS 2093165-00-3

SKU:MF-0121596-01

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  • Bioactivity

    PBD-monoamide, a modified pyrrolobenzodiazepine (PBD) dimer, functions as an ADC cytotoxin. It is utilized in synthesizing DHES0815A (an HER2 ADC) and possesses DNA-binding activity that reduces cell viability [1].

  • Target

    ADC Cytotoxin

  • Related Pathways

    Antibody-drug Conjugate/ADC Related

  • CAS Number

    2093165-00-3

  • Molecular Formula

    C33H36N4O8

  • Molecular Weight

    616.66

  • SMILES

    O=C1C=2C(=CC(OCCCCCOC3=C(OC)C=C4C(=C3)N=C[C@]5(N(C4=O)CC(=C)C5)[H])=C(OC)C2)NC(=O)[C@]6(N1CC(=C)C6)[H]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound