PBP10 - CAS 794466-43-6

Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility. Also exhibits antiviral activity against influenza viruses via inhibition of viral-induced ERK activation.

Antibacterial

Microbiology/Virology

794417

C84H126N24O15

1712.1

C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CCCNC(=N)N)C(O)=O)=O)CCCNC(=N)N)=O)=O)CCCCN)=O)[C@H](C)C)=O)CCC(N)=O)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCC(N)=O)(=O)C2=C(C=3C4=C([O+]=C5C3C=CC(N(CC)CC)=C5)C=C(N(CC)CC)C=C4)C=CC=C2

-20°C

Ice Packs

Peptide