PBS-1086 - CAS 1246668-32-5

PBS-1086 is a novel dual inhibitor of the canonical and noncanonical NF-κB pathways, increasing the magnitude and duration of initial EGFR inhibitor response in multiple NSCLC models, decreasing PDHK1 expression, and suppressing phosphorylation of the PDHK1 protein substrate PDHA1 in a panel of PTEN-deficient cell lines.

Others

Others

1246631

C16H12N2O5

312.28

OC1C2C(O2)C(=O)C=C1NC(=O)C3=CC=4C(NC3=O)=CC=CC4

-20°C

Ice Packs

Small Compound