PBT434 methanesulfonate - CAS 2387898-69-1

PBT434 methanesulfonate is an orally active, potent α-synuclein aggregation inhibitor with the ability to cross the blood-brain barrier. Acting as an iron chelator, it modulates transcellular iron trafficking, inhibits iron-mediated redox activity, and prevents iron-mediated aggregation of α-synuclein. PBT434 methanesulfonate also safeguards against the loss of substantia nigra pars compacta neurons (SNpc), showing promise for Parkinson's disease (PD) research.

Others

Others

2387828

C13H17Cl2N3O5S

398.26

O=C1C=2C(Cl)=CC(Cl)=C(O)C2N=C(N1C)CNCC.O=S(=O)(O)C

-20°C

Ice Packs

Small Compound