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Molfinity

PCSK9 autophagic degrader 2 - CAS 2974497-11-3

PCSK9 autophagic degrader 2 - CAS 2974497-11-3

MF-0114701-01

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Product Details

  • Bioactivity

    PCSK9 autophagic degrader 2 (W6) is an autophagosome-targeting agent for PCSK9, with a DC50 value of 20.6 nM. It exhibits effects comparable to anti-atherosclerotic treatments and has a binding constant (KD) with LC3B of 2.5 μM.

  • Target

    ATTECs

  • Related Pathways

    PROTAC

  • CAS Number

    2974483

  • Molecular Formula

    C39H41Br2IN4O8S

  • Molecular Weight

    1012.54

  • SMILES

    O=C1C(=CC2=CC(Br)=C(O)C(Br)=C2)C3=CC(I)=CC=C3N1CCOCCOCCOCCOC=4C=C5C(=CC4OC)CCNC5(C)CC(=O)NC6=NC=CS6

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    PROTAC