PCSK9-IN-29 - CAS 1233353-86-0

PCSK9-IN-29 serves as a lipid-lowering agent that enhances the expression of low-density lipoprotein receptor (LDLR) protein and reduces PCSK9 protein expression in hepG2 cells. Additionally, in crab-eating macaques on a high-fat diet, it lowers serum LDL-C, TC, and liver enzyme ALT levels, reduces body weight and fat, and boosts bone mineral content. PCSK9-IN-29 is useful for studies involving non-alcoholic fatty liver disease and obesity.

LDLR

Metabolism

1233267

C26H26FNO6S

499.55

O=S(=O)(OC=1C(OC)=CC=C2C1CN3CCC4=CC(OC)=C(OC)C=C4C3C2)C=5C=CC=C(F)C5

-20°C

Ice Packs

Small Compound