PCTR1 - CAS 1810710-59-8

Protectin conjugates in tissue regeneration 1 (PCTR1) is a specialized pro-resolving mediator (SPM) synthesized from docosahexaenoic acid . DHA is oxidized to 16S,17S-epoxy-protectin, which is then converted to PCTR1 by glutathione S-transferase. PCTR1 levels increase during resolution of acute microbial-induced peritonitis in mice. PCTR1 (30 ng, i.p.) administration 12 hours post-infection increases macrophage numbers and activity and shortens the resolution phase of inflammation by 57%. It also reduces the levels of PGE2 , PGD2 , and TXB2 in peritoneal exudates.

Others, Antibacterial

Others, Microbiology/Virology

1810643

C32H47N3O9S

649.8

[C@@H](CS[C@H](/C=C/C=C/C=C\C/C=C\C/C=C\CCC(O)=O)[C@H](C/C=C\CC)O)(NC(CC[C@@H](C(O)=O)N)=O)C(NCC(O)=O)=O

-20°C

Ice Packs

Small Compound