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Molfinity

PD-089828 - CAS 179343-17-0

PD-089828 - CAS 179343-17-0

MF-0044773-01

$33.17 USD
$33.17 USD
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Product Details

  • Bioactivity

    PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 μM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 = 0.18 μM)

  • Target

    FGFR, EGFR, PDGFR, Src

  • Related Pathways

    Angiogenesis, Tyrosine Kinase/Adaptors, JAK/STAT signaling

  • CAS Number

    179326

  • Purity

    0.9739

  • Molecular Formula

    C18H18Cl2N6O

  • Molecular Weight

    405.28

  • SMILES

    CC(C)(C)NC(=O)Nc1nc2nc(N)ncc2cc1-c1c(Cl)cccc1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound