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PD-1/PD-L1-IN-14 - CAS 2499965-12-5
PD-1/PD-L1-IN-14 - CAS 2499965-12-5
SKU:MF-0043699-01
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$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
PD-1/PD-L1-IN-14 (compound 17) is an inhibitor of PD-1/PD-L1 interaction (IC50=27.8 nM) that promotes PD-L1 dimerization, endocytosis, and degradation.
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Target
PD-1/PD-L1, Others
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Related Pathways
Cell Cycle/Checkpoint, Apoptosis, Immunology/Inflammation, Others
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CAS Number
2499948
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Molecular Formula
C24H24N4O2
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Molecular Weight
400.47
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SMILES
CC1=C(C=2OC(NC3=CC(CNCCO)=CC=C3)=NN2)C=CC=C1C4=CC=CC=C4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound