PD-1/PD-L1-IN-26 - CAS 2966090-78-6

PD-1/PD-L1-IN-26 (Compound II-14) is a potent PD-1/PD-L1 inhibitor with an IC50 of 0.0380 μM. It enhances the immune microenvironment by promoting CD4+ T cell infiltration into tumor tissues, suggesting its potential application in cancer research [1].

PD-1/PD-L1

Cell Cycle/Checkpoint, Immunology/Inflammation, Apoptosis

2966006

C43H52N4O8

752.89

CC1=C(C=CC=C1C2=CC(=CC=C2)OCCCN3CCC(CC3)CO)COC4=CC(=C(C=C4)CNC(CO)(CO)CO)OCC5=NN=C(O5)C6=CC=CC=C6

-20°C

Ice Packs

Small Compound