PD-1/PD-L1-IN-27 - CAS 2891831-47-1

PD-1/PD-L1-IN-27 is a potent inhibitor of PD-1/PD-L1, with an IC50 of 134 nM, and demonstrates antitumor effects with minimal T cell cytotoxicity. It activates CD8+ T cells and mitigates T cell exhaustion [1].

PD-1/PD-L1

Immunology/Inflammation, Apoptosis, Cell Cycle/Checkpoint

2891783

C44H35NO6

673.75

CC1=C(C=CC=C1C2=CC=CC=C2)COC3=CC(=C(C=C3)CN4CC5=CC=CC=C5C[C@@H]4C(=O)O)OC6=CC(=O)OC7=C6C=CC8=CC=CC=C87

-20°C

Ice Packs

Small Compound