PD-1/PD-L1-IN-29 - CAS 2665734-13-2

PD-1/PD-L1-IN-29 (S4-1) is a potent inhibitor of the PD-1/PD-L1 interaction with an IC50 value of 6.1 nM. It effectively binds to PD-L1, promoting its dimerization and internalization, enhancing its localization to the endoplasmic reticulum, and demonstrating anticancer activity.

Others, PD-1/PD-L1

Others, Apoptosis, Cell Cycle/Checkpoint, Immunology/Inflammation

2665719

C26H24N2O6

460.48

O=C1N(C(=O)C=2C1=CC(CN[C@H](C(O)=O)CO)=C(OC)C2)C3=C(C)C(=CC=C3)C4=CC=CC=C4

-20°C

Ice Packs

Small Compound