PD-1/PD-L1-IN-33 - CAS 2975602-78-7

PD-1/PD-L1-IN-33 (Compound N11), a PD-1/PD-L1 inhibitor with an IC50 of 6.3 nM, effectively impedes the interaction between PD-1 and PD-L1. It enhances T-cell proliferation, activation, and infiltration within tumor environments, thereby exhibiting immunomodulatory and anticancer properties [1].

PD-1/PD-L1

Immunology/Inflammation, Cell Cycle/Checkpoint, Apoptosis

2975517

C26H27N5O

425.53

C(NC(CO)(C)C)C1=CC2=C(C(N3C=4C(CC3)=C(C=CC4)C5=CC=CC=C5)=NC=N2)N=C1

-20°C

Ice Packs

Small Compound