PD-1/PD-L1-IN-9 - CAS 2628506-54-5

PD-1/PD-L1-IN-9, with an IC50 of 3.8 nM, is a potent and orally active inhibitor of the PD-1/PD-L1 interaction. It enhances the immune cells' ability to kill tumor cells and demonstrates significant antitumor activity in vivo in a CT26 mouse model.

PD-1/PD-L1

Apoptosis, Cell Cycle/Checkpoint, Immunology/Inflammation

2628447

0.9992

C22H24N2O2

348.44

COc1nc(ccc1CNCCO)-c1cccc(c1C)-c1ccccc1

-20°C

Ice Packs

Small Compound