PD 109488 - CAS 103733-49-9

PD 109488 is a metabolite of quinapril and is a derivative of Quinapril that acts as an ACE inhibitor. Inhibition of ACE prevents the conversion of signaling peptide angiotensin I into angiotensin II, which acts as a potent vasoconstrictor. Reduced levels of angiotensin II also reduces the amount of aldosterone that is expressed due to RAAS signaling.

Others, Drug Metabolite

Others, Metabolism

103675

C25H28N2O4

420.5

[C@@H](C(OCC)=O)(CCC1=CC=CC=C1)N2C(=O)[C@]3(N(C(=O)[C@@H]2C)CC=4C(C3)=CC=CC4)[H]

-20°C

Ice Packs

Small Compound