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PD 123319 ditrifluoroacetate - CAS 136676-91-0

PD 123319 ditrifluoroacetate - CAS 136676-91-0

SKU:MF-0023217

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  • Bioactivity

    PD 123319 ditrifluoroacetate is a selective, non-peptide angiotensin II type 2 (AT2) receptor antagonist, and PD 123319 ditrifluoroacetate demonstrates potent activity with IC50 values of 34 nM in rat adrenal tissue and 210 nM in rat brain, thereby providing a valuable pharmacological tool for elucidating AT2 receptor function in cardiovascular and renal physiology and supporting research in hypertension and related disorders.

  • Target

    RAAS

  • Related Pathways

    Endocrinology/Hormones

  • CAS Number

    136585

  • Molecular Formula

    C35H34F6N4O7

  • Molecular Weight

    736.66

  • SMILES

    OC(=O)C(F)(F)F.OC(=O)C(F)(F)F.CN(C)c1ccc(Cn2cnc3CN([C@@H](Cc23)C(O)=O)C(=O)C(c2ccccc2)c2ccccc2)cc1C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound