PD 130908 - CAS 131505-02-7

PD 130908 is an analogue of RSU 1069 with effective hypoxic cytotoxin, but less potent than RSU 1069. Toxicity toward hypoxic tumor cells in vivo is demonstrated by clamping tumors (for 60 min) following administration of PD 130908. Systemic toxicity is substantially reduced following oral drug administration. Further, doses achievable following fractionated drug treatments are sufficiently high to produce significant levels of radiosensitization.

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Others

131505-02-7

C8H14Br2N4O2

358.03

Br.O=N(=O)C1=NC=CN1CCCNCCBr

-20°C

Ice Packs

Small Compound