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Molfinity

PD-161570 - CAS 192705-80-9

PD-161570 - CAS 192705-80-9

MF-0016374-01

$32.42 USD
$32.42 USD
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Product Details

  • Bioactivity

    PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. It also inhibits the PDGFR, EGFR, and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively.

  • Target

    TGF-beta/Smad, Src, PDGFR, FGFR, EGFR

  • Related Pathways

    Stem Cells, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    192616

  • Purity

    0.9992

  • Molecular Formula

    C26H35Cl2N7O

  • Molecular Weight

    532.51

  • SMILES

    CCN(CC)CCCCNc1ncc2cc(c(NC(=O)NC(C)(C)C)nc2n1)-c1c(Cl)cccc1Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound