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Molfinity

PD 166326 - CAS 185039-91-2

PD 166326 - CAS 185039-91-2

SKU:MF-0140599-01

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  • Bioactivity

    PD166326, a pyridopyrimidine-type inhibitor of receptor tyrosine kinases, demonstrates antileukemic activity with IC50 values of 6 nM for Src and 8 nM for Abl. [1] [2].

  • Target

    BCRP, Others, Src

  • Related Pathways

    Membrane transporter/Ion channel, Others, Angiogenesis, Tyrosine Kinase/Adaptors

  • CAS Number

    184946

  • Molecular Formula

    C21H16Cl2N4O2

  • Molecular Weight

    427.28

  • SMILES

    O=C1C(=CC=2C(N1C)=NC(NC3=CC(CO)=CC=C3)=NC2)C4=C(Cl)C=CC=C4Cl

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound