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Molfinity

PD 90780 - CAS 77422-99-2

PD 90780 - CAS 77422-99-2

SKU:MF-0023244-01

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  • Bioactivity

    PD 90780 is a non-peptide antagonist of nerve growth factor (NGF) that interacts with NGF and prevents it from binding to p75NTR, inhibiting the NGF-p75NTR interaction with IC50s of 23.1 and 1.8 μM in PC12 cells and PC12nnr5 cells, respectively.

  • Target

    Others, Trk receptor

  • Related Pathways

    Tyrosine Kinase/Adaptors, Others

  • CAS Number

    77321

  • Purity

    0.9922

  • Molecular Formula

    C19H14N4O4

  • Molecular Weight

    362.34

  • SMILES

    Cn1c2cc(nn2c(=O)c2cc(NC(=O)c3ccccc3)ccc12)C(O)=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound